LookCloser.aipublic supplement evidence
Exact product checked · GTIN 0074098522550921st Century · checked Jul 25, 2026USPTO returned 3 exact supplement-class owner records · inspect the identity trail
Quick read · 21st Century

21st Century Niacinamide 500 mg Prolonged Release…

Checked against public sources on July 25, 2026 · LookCloser does not sell or recommend supplements.

110tablets

Does the marketing hold up?

FDA recall appears in this brand's history An exact-product recall is a direct signal. A different product from the same firm is company context, not a strike against this item.

Is the dose real?Panel read — 2 ingredients listed
What a serving costsNo exact-match price found
Is it tested?No testing claim made
Who’s behind it?No exact match in USPTO — see checks below
Is it the real thing?Barcode matches outside records
Trouble on record?Brand history — not this product

“Couldn’t verify” means we looked and found no public proof — not a mark against the product. Most supplement claims cannot be independently verified by anyone, so grey is the normal state of this industry.

1◖ partly confirmedno contradictions · brand-level recall on file
Marketing claims, checked

The checks, one by one

The public sources did not settle the marketing promises on this label.

Partly confirmed1

“Absorption* Good For You TRUSTED QUALITY GMP Certified & FDA Registered”

“GMP-certified” describes factory processes, not what is in the bottle. The claim does not name a certifier or public register that a shopper can check.

Evidence →

Ingredient research can support context, but it is not a trial of this exact product.

Quick read · 4 useful findings

What is worth knowing.

Headlines first. Open evidence only when you want the source trail.

Needs explanationAny trouble in public records?

FDA recall appears in this brand's history

An exact-product recall is a direct signal. A different product from the same firm is company context, not a strike against this item.

Evidence and sources

Brand-level context only, not a finding about this product. Twenty-First Century Healthcare, Inc recalled a different or not-exactly-bound product on 2021-05-07: “A small quantity of bottles of Vitamin D3 125 mcg ((5000 IU) 100 ct. were mislabeled as Vitamin D3 25 mcg (1000 IU). …

Locked evidence record →Open the full source-linked finding
Public contextWho is behind it?

Registered owner records: Twenty-First Century Laboratories, Inc. · Twenty-First Century HealthCare, Inc. · Twenty First Century Nutritional Products, Inc.

The public ownership record is ambiguous. We show the exact candidates instead of choosing one by name similarity.

Evidence and sources

USPTO returned multiple live supplement-class records for the exact brand wordmark: Twenty-First Century Laboratories, Inc., Twenty-First Century HealthCare, Inc., Twenty First Century Nutritional Products, Inc.. These records answer who owns registrations for the brand; the sepa…

Locked evidence record →Open the full source-linked finding
Checks outIs the label honest?

Every ingredient shows its amount · 2 ingredients listed.

Every ingredient shows its real amount — nothing is hidden in a proprietary blend.

Evidence and sources

The panel gives a per-ingredient amount rather than hiding quantities inside a proprietary blend, so each one can be compared to published research.

Locked evidence record →Open the full source-linked finding
What remains open 2
  • No matched to this exact product public label filing is saved in this record.
  • Barcode checksum is valid; no independent product record was found.

These are evidence gaps, not strikes against the product.

Who owns the brand wordmark?

The brand has 3 exact supplement-class records

These are the USPTO records behind the brand name. We show them all rather than choosing one by similarity.

🇺🇸Twenty-First Century Laboratories, Inc.

ARIZONA, USA · Registration 3645342

2119 South Wilson Street, Tempe, ARIZONA 85282, UNITED STATES

Goods covered by this record

IC 005: vitamins, mineral supplements, dietary supplements, nutritional supplements, weight loss supplements, herbal supplements, herbal teas for weight loss, vitamins for pets, nutritional supplements for pets, dietary supplements for pets, and herbal supplements for pets.

🇺🇸Twenty-First Century HealthCare, Inc.

ARIZONA, USA · Registration 4085491

443 West Alameda Drive, Tempe, ARIZONA 85282, UNITED STATES

Goods covered by this record

IC 005: Vitamins; mineral supplements; dietary supplements; nutritional supplements; herbal supplements [ ; weight loss supplements; vitamins for pets; nutritional supplements for pets; dietary supplements for pets; herbal supplements for pets; food supplements for pets; ear drops for pets; ear cleaning pads for pets impregnated with medicated skin care cleaners; ear preparations in the nature of medicated powders for pets to eliminate odor and to relieve itching and irritation; first aid kits for pets; self-adhering flexible bandages for pets; pain relief medication for pets; medicated pet shampoo; anti-itch preparations for pets, namely, medicated sprays, powders, lotions and shampoo; medicated lotions and pads to remove tear and saliva stains from the coats of pets; styptic preparations, namely, powders, for pets; and hydrocortisone preparations, namely, anti-itch lotions, sprays and shampoo, for pets ].

🇺🇸Twenty First Century Nutritional Products, Inc.

ARIZONA, USA · Registration 1790110

2445 West 12th Street, Tempe, ARIZONA 85281, UNITED STATES

Goods covered by this record

IC 005: vitamins, herbal remedies and nutritional supplements.

This answers who owns registrations for the brand wordmark. It does not by itself prove which entity made, imported, or sold this specific product. Open USPTO source ↗

Where it sells

Price check for this exact product

Amazon

Exact UPC/GTIN match
$5.49

matching UPC/GTIN · checked Jul 26, 2026

View on Amazon ↗

iHerb

Exact UPC/GTIN match
$5.49

4.6/5 · 4,524 ratings

matching UPC/GTIN · checked Jul 25, 2026

View on iHerb ↗

Target

Exact UPC/GTIN match
$9.01

matching UPC/GTIN · checked Jul 25, 2026

View on Target ↗

Walmart

Not confirmed
No exact listing saved

Search results remain not linked to this exact product until this retailer publishes the matching UPC/GTIN.

Search Walmart ↗

Same UPC/GTIN observed across 3 sellers. Amazon was lowest at $5.49; Target was highest at $9.01 — a $3.52 range at check time.

No official brand storefront is confirmed in this record. That is neutral, but it prevents a direct brand-price, label, review, and document check.

Reference prices only · no affiliate links · every compared seller must publish the matching UPC/GTIN.

Want to inspect the evidence?

The full report shows every source, the exact unresolved question, and the documentation that would settle it.

Read / share full evidence →

Record built July 25, 2026. Sources: source listing observed at check time · USPTO Trademark Search · Keepa exact-listing history · NIH / published research · certification and regulator records where available. LookCloser publishes evidence and gaps; it does not advise for or against any supplement. Evidence-based corrections welcome.